Project 1
Identification of the cell-specific contribution of the P2X7 receptor to seizure-induced pathology and epilepsy development
PhD candidate: James Morgan
Project Supervisor: Dr Tobias Engel
Collaborators: Prof Felix Rosenow, Dr John Ryan and Prof Miguel Diaz-Hernandez
Location: Royal College of Surgeons in Ireland
Project 2
P2X7 receptor signalling during seizures and identification of a seizure-specific P2X7R signature in blood
PhD candidate: Giorgia Conte
Project Supervisor: Dr Tobias Engel
Collaborators: Prof Annette Nicke, Prof Nicholas Dale and Prof Felix Rosenow
Location: Royal College of Surgeons in Ireland
Project 3
Identification of novel disease-specific P2X7R down-stream targets in schizophrenia and epilepsy
PhD candidate: Antonio Ramirez-Fernandez
Project Supervisor: Prof Annette Nicke
Collaborators: Prof Antonio Garcia, Dr Tobias Engel and Prof Beata Sperlagh
Location: University of Ludwig Maximilans, Germany
Project 4
Targeting of the purinergic P2X7 receptor to treat Alzheimer’s disease
PhD candidate: Caterina Di Lauro
Project Supervisor: Prof Miguel Diaz-Hernandez
Collaborators: Dr Miguel Medina, Dr Tobias Engel and Prof Andras Dinnyes
Location: University Complutense Madrid, Spain
Project 5
Blood purines as novel diagnostic for pre-clinical Alzheimer’s disease and identification of P2X7R-dependent down-stream targets in Alzheimer’s disease
PhD candidate: Carolina Bianchi
Project Supervisor: Prof Miguel Diaz-Hernandez
Collaborators: Dr Tobias Engel, Dr Miguel Medina and Dr Benjamin Seibt
Location: University Complutense Madrid, Spain
Project 6
P2X7R signalling in the brain during schizophrenia and blood purine changes as novel diagnostics and prognostics for schizophrenia
PhD candidate: Lumei Huang
Project Supervisor: Prof Beata Sperlagh
Collaborators: Prof Nicholas Dale, Prof Istvan Bitter and Prof Miguel Diaz-Hernandez
Location: Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary
Project 7
Pathological contribution of the ATP-gated purinergic P2X7 receptor to the pathogenesis of schizophrenia
PhD candidate: Paula Mut Arbona
Project Supervisor: Prof Beata Sperlagh
Collaborators: Prof Istvan Bitter, Prof Jose Lucas and Prof Antonio Garcia
Location: Institute of Experimental Medicine, Hungarian Academy of Sciences, Hungary
Project 8
The P2X7 receptor as drug target in depression and blood purines as novel diagnostic and prognostics in depression
PhD candidate: Lidia Urbina
Project Supervisor: Dr Jan Deussing
Collaborators: Prof Martin E Keck, Prof Beata Sperlagh and Dr Benjamin Seibt
Project 9
The purinergic P2X7 receptor in diagnosis, prognosis and treatment in Huntington’s disease
PhD candidate: Ivana Ollà
Project Supervisor: Prof Jose Lucas
Collaborators: Dr Jose Lopez, Dr Benjamin Seibt and Dr Tobias Engel
Project 10
Analysis of P2X7 receptor function and effects of P2X7R antagonism on neuronal differentiation and connectivity in neuronal networks generated from Alzheimer’s disease patient derived pluripotent stem cells
PhD candidate: Linda Francistiova
Project Supervisor: Prof Andras Dinnyes
Collaborators: Dr Miguel Medina, Dr Tobias Engel and Prof Annette Nicke
Location: Bio Talentum, Hungary
Project 11
Development of a novel in vivo biosensor for neuroscience applications
PhD candidate: Martina Mengoni
Project Supervisor: Prof Nicholas Dale
Collaborators: Dr Tobias Engel, Prof Felix Rosenow and Dr Miguel Medina
Location: Sarissa Biomedical LTD, UK
Project 12
Biosensor approaches to the study of purinergic signalling during acute and chronic brain diseases
PhD candidate: Monica Garcia Durillo
Project Supervisor: Prof Bruno Frenguelli
Collaborators: Dr Tobias Engel, Prof Beata Sperlagh and Prof Andras Dinnyes
Location: Sarissa Biomedical LTD, UK
Project 13
The ATP-gated P2X7 receptor as novel treatment target in amyotrophic lateral sclerosis
PhD candidate: Cristina Ruiz
Project Supervisor: Prof Antonio Garcia
Collaborators: Prof Miguel Diaz-Hernandez, Dr Tobias Engel and Prof Beata Sperlagh
Location: Foundation Teofilo Hernando, Spain
Project 14
Development of a novel blood brain barrier and brain stable P2X7R antagonist
PhD candidate: Francesco Calzaferri
Project Supervisor: Prof Antonio Garcia
Collaborators: Prof Annette Nicke, Dr Jan Deussing and Prof Andras Dinnyes
Location: Foundation Teofilo Hernando, Spain
